Susie Isaacs is best known for being the first woman to win the World Series of Poker Ladies Championship back-to-back in 1996 and 1997. In 1998, she placed 10th in the WSOP $10,000 main event vying for the million dollar first prize. She became the second woman in history to accomplish such an outstanding finish.

In the 2006 WSOP main event she managed to place in the top five percent out of a record breaking field of 8,773. In the 2007 Ladies World Championship Event, she placed 35th out of a record breaking field of 1,279 making her the highest scoring woman in that event in World Series history. Susie is a professional tournament poker player. She has won various titles and placed in the money numerous times over the years. She was invited to play on the Pro Poker Tour of the World Poker Tour in 2005.

She is the most published female writer on the subject of poker in the world. Since 1988, she has written poker related articles and stories under the title of “Chip Chatter” for a variety of gaming magazines and publications. Books by Susie Isaacs include: MsPoker: Up Close and Personal (out of print.) The follow-up, MsPoker: I'm Not Bluffing is a two-book series. Book One includes her personal story and great true stories from the green felt which she has collected through the years. Book Two is solely poker tournament strategy. Her other poker-related books are 1,000 Best Poker Strategies and Secrets, and Queens Can Beat Kings. Her latest literary offering is her first novel titled, White Knight, Black Nights, Poker is Skill, Life is the Gamble. Susie sold the movie rights to her novel, "White Knight, Black Nights" in the summer of 2013.

Susie has taught poker to many individuals and has testimonials as to the improvement in their game. She has taught seminars at Lake Austin Spa in Austin, Texas, Ocean’s Eleven Casino, Hollywood Park Casino, and Orange Park Casino. Currently she is a regular instructor for the High Heels Poker Academy.

Susie Isaacs was formally inducted into the Women in Poker Hall of Fame at Binion's Casino in Las Vegas, on February 2, 2008. The WIPHOF was designed to honor women in poker who have acquired prominence and who also have made contributions to the poker world.

In April of 2008 Susie was recognized for her tremendous accomplishments in Poker and was inducted into the Seniors Hall of Fame.

In the fall of 2013, Susie being one of the most recognizable faces in poker was invited to play on the team of the new Seniors Poker Tour.

Women in Poker Hall of Fame 2008 Inductees into the Women in Poker Hall of Fame: Left to Right: Marsha Waggoner, Linda Johnson, Susie "Ms. Poker" Isaacs, and Barbara Enright
Susie Isaacs Trophy Susie Isaacs “Ms Poker” with another first place finish.
Susie is the first woman to win back-to-back WSOP Ladies Championship bracelets.